C.B. Anfinsen, John T. Edsall, Frederic M. Richards, David's Accessory Folding Proteins PDF

By C.B. Anfinsen, John T. Edsall, Frederic M. Richards, David S. Eisenberg and George Lorimer (Eds.)

ISBN-10: 0120342448

ISBN-13: 9780120342440

Studies present themes within the box of protein chemistry. the themes lined contain the constitution and mechanism of heat-shock-related proteins, the position of prolylisomerases in protein folding, and the mechanism of enzymic and nonenzymic prolylcis-transisomerization.

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Hung, S. H. , and Sigal, N. H. Nature (London) 341,755-757. Stein, R. L. (1991). Curr. Biol. 1, 234-236. Steinberg, I . , Harrington, W. , and Katchalski, E. J. Am. Chem. Sac. 82, 5263-5279. Stewart, W. , and Siddall, T. H. (1970). Chem. Rev. 70, 517-551. , and Suzuki, M. (1989). Nature (London) 337, 473-475. Van Duyne, G. , Standaert, R. , Karplus, P. , Schreiber, S. , and Clardy, J. (1991). Science 252, 839-842. , and Braun, W. (1991). Science 254, 953-954. PROLYL ISOMERASES: ROLE IN PROTEIN FOLDING By FRANZ X.

87, 2304-2308. Love, A. , Alger, T. , and Olsen, R. K. J. Phys. Chem. 76, 853-855. Lumry, R. (1986). I n “The Fluctuating Enzyme” (G. R. ), p. 6. Wiley, New York. , and Rajender, S. (1970). Eiopolymers 9, 1125-1227. Martin, R. B. J . Chem. , Chem. Commun. pp. 793-794. McCall, J. M. J. Med. Chem. 18, 549-552. Michnick, S. , Rosen, M. , Wandless, T. , and Schreiber, S. L. (1991). Science 252, 836-839. 24 ROSS L. STEIN Moore, J. , Peattie, D. , Fitzgibbon, M. , and Thompson, J. A. Nature (London) 351,248-250.

This function of prolyl isomerases in protein folding is the major topic of this review. Mechanistic aspects of the enzymes and the catalyzed reactions are described by Stein elsewhere in this volume. Here we discuss first the importance of prolyl isomerization reactions as slow, rate-limiting steps of folding and their interdependence with other events in protein folding. Then, experimental data on the catalysis by prolyl isomerases of various slow in vitro protein folding reactions are reviewed.

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Accessory Folding Proteins by C.B. Anfinsen, John T. Edsall, Frederic M. Richards, David S. Eisenberg and George Lorimer (Eds.)


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